The drug sildenafil (Viagra) increases cGMP levels, so which enzyme is most likely inhibited by Viagra?
A) Phosphodiesterase
B) Protein kinase
C) Guanylyl cyclase
D) Protein phosphatase
E) ATPase

Question

Quizplus · Accepted Answer

Sildenafil (Viagra) inhibits the enzyme phosphodiesterase, which is responsible for the degradation of cGMP. This leads to an increase in cGMP levels, which promotes smooth muscle relaxation and increased blood flow, leading to an erection.

The Drug Sildenafil (Viagra) Increases CGMP Levels, So Which Enzyme