A Theoretical Enzyme, Anyase, Catalyzes the Same Reaction Using Five

A theoretical enzyme, anyase, catalyzes the same reaction using five different substrates.The dissociation constants for these substrates and the enzyme are listed below.Which substrate will produce the greatest concentration of anyase-substrate complex?

A) Substrate A, K_D = 10^-7 M
B) Substrate B, K_D = 10^-4 M
C) Substrate C, K_D = 10⁰ M
D) Substrate D, K_D = 10⁴ M
E) Substrate E, K_D = 10⁷ M