Which Statement About Metabolic Pathways Is Incorrect

Which statement about metabolic pathways is incorrect?

A) Chemical transformations occur in a series of separate chemical reactions.
B) A specific enzyme catalyzes each transformational step.
C) In eukaryotes, all metabolic reactions occur in the cytoplasm.
D) Inhibitors that target some key enzymes in a pathway can slow the rate of reaction.
E) Activators that target some key enzymes in a pathway can increase the rate of reaction.