To test an individual's genotype for the sickle-cell mutation, a _______ test would use a probe for normal hemoglobin and a probe for the sickle-cell mutation.

Question

Quizplus · Accepted Answer

The allele-specific oligonucleotide hybridization technique is used to detect specific mutations in DNA, such as the sickle-cell mutation. It involves using probes that are complementary to the normal and mutant versions of the gene, and detecting which probe binds to the target DNA sequence. This technique is commonly used in diagnostic testing for genetic diseases.

To Test an Individual's Genotype for the Sickle-Cell Mutation, a _______