If HIV is mutated such that its tat protein is less able to bind to mRNA, the most likely result will be
A) more initiation of transcription.
B) less initiation of transcription.
C) the termination of more partial transcripts, and thus the making of fewer complete transcripts.
D) the termination of fewer partial transcripts, and thus the making of more complete transcripts.
E) a reduction in the stability of complete transcripts.

Question

Quizplus · Accepted Answer

The tat protein in HIV is crucial for the efficient elongation of viral transcripts by promoting RNA polymerase II's processivity. If tat's ability to bind to mRNA is compromised, it would lead to premature termination of transcripts, resulting in more partial transcripts and fewer complete ones.

If HIV Is Mutated Such That Its Tat Protein Is