Which Statement About Metabolomics Is False

Which statement about metabolomics is false?

A) The metabolome is determined directly from the proteome in a one-to-one relationship.
B) The metabolome includes both primary and secondary metabolites.
C) Results from metabolomics studies argue against genetic determinism.
D) Analysis of the metabolome requires chemical methods for separating small molecules.
E) Metabolomics is the quantitative description of all of the small molecules in an organism.