Selectable markers are usually used in studies involving transformation because
A) vectors are typically small in comparison to the host cell.
B) host cells are typically prokaryotic.
C) host cells are typically eukaryotic.
D) transformation is usually very efficient.
E) transformation is usually very inefficient.

Question

Quizplus · Accepted Answer

Transformation is usually very inefficient, meaning that only a small fraction of cells take up the vector and express its genes. Selectable markers help identify and select for those cells that have successfully incorporated the foreign DNA, making them crucial for distinguishing transformed cells from those that have not been transformed.

Selectable Markers Are Usually Used in Studies Involving Transformation Because