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Puffer Fish Are Resistant to Poisoning by TTX, a Sodium

Question 102

Short Answer

Puffer fish are resistant to poisoning by TTX, a sodium channel toxin that they produce as a defensive mechanism.TTX cannot bind to puffer fish sodium channels, because _______ nucleotide substitutions in the sodium channel gene have altered the protein structure such that the TTX binding site is lost without affecting the function of the sodium channel.

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