Which substance is most likely responsible for fever during inflammation?

Question

Quizplus · Accepted Answer

Cytokines, such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha), are known to be potent pyrogens, which means they can cause fever by acting on the hypothalamus in the brain. During inflammation, immune cells release cytokines in response to infection, injury, or other stimuli, which can trigger a fever response as part of the body's defense mechanisms.

Which Substance Is Most Likely Responsible for Fever During Inflammation