Which Statement About Cellular Respiration Is True

Which statement about cellular respiration is true?

A) Cells need ATP to produce oxygen via cellular respiration.
B) Respiratory gases are exchanged between the respiratory medium (air or water) and the internal body fluids of an animal via active transport.
C) Carbon dioxide is an end product of cellular respiration that must be removed from the body.
D) In a gas exchange system, a perfusion mechanism moves air or water across the outer surface of the respiratory membrane.
E) In a gas exchange system, a ventilation mechanism moves extracellular fluids across the inner surface of the respiratory membrane.