Beadle and Tatum discovered that metabolic pathways are studied most effectively using which of the following techniques?
A) using multiple gene mutations resulting in nonfunctional enzymes specific to a metabolic pathway
B) adding intermediates to a metabolic pathway
C) removing all intermediates of a metabolic pathway
D) using single gene mutations resulting in nonfunctional enzymes specific to a metabolic pathway

Question

Quizplus · Accepted Answer

Using single gene mutations resulting in nonfunctional enzymes specific to a metabolic pathway allowed Beadle and Tatum to identify which genes were responsible for producing specific enzymes in the pathway. This led to the one gene-one enzyme hypothesis, which later became the one gene-one polypeptide hypothesis.

Beadle and Tatum Discovered That Metabolic Pathways Are Studied Most