Knockout mice have been genetically altered to knock out specific genes. How are these mice most often used in research?
A) to study DNA replication in the defective genes (those that have been altered)
B) to determine the role of proteins coded for by those genes that are knocked out
C) to examine defects in DNA structure in those regions that have been altered
D) to study the effect of radiation on DNA

Question

Quizplus · Accepted Answer

Knockout mice are most often used to determine the role of proteins coded for by genes that are knocked out. By observing the behavior and phenotype of the knockout mice, researchers can infer the function of the gene that has been deleted. This information can give insights into human diseases that are associated with mutations in the same gene.

Knockout Mice Have Been Genetically Altered to Knock Out Specific