The first documented case of drug tolerance had to do with someone named __________.

Question

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King Mithridates VI of Pontus was the first person to document the concept of drug tolerance. He believed that by taking small doses of various poisons, he could build up an immunity to them and protect himself from assassination. He reportedly took small doses of poison every day to build up this immunity, which is now known as Mithridatism.

The First Documented Case of Drug Tolerance Had to Do