The ratio of the LD₁ over the ED₉₉ is called the __________.

Question

Quizplus · Accepted Answer

The ratio of the LD₁ over the ED₉₉ is called the margin of safety. It is the measure of the relative safety of a drug and indicates how much higher the therapeutic dose is compared to the toxic dose. A higher margin of safety means the drug is safer to use because a larger difference exists between the therapeutic and toxic doses. Therefore, option B (margin of safety) is the correct answer. Option A (therapeutic index) is similar to the margin of safety but specifically refers to the ratio of the dose that provides therapeutic benefit to the dose that causes toxicity. Option C (effective dose for a particular drug effect) refers to the dose required to produce a particular effect in a given percentage of the population. Option D (lethal dose) refers to the dose that causes death in a specified percentage of test animals or humans.

The Ratio of the LD1 Over the ED99 Is Called

The Ratio of the LD₁ Over the ED₉₉ Is Called