DNA polymerase I is extremely accurate in its ability to make a complementary copy of the template. The key activity that allows the polymerase to be so accurate is the

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The 5' => 3' exonuclease activity of DNA polymerase I allows it to proofread and remove any incorrect nucleotides that have been added to the growing strand before continuing with new nucleotides. This activity greatly improves the accuracy of the newly synthesized DNA strand.

DNA Polymerase I Is Extremely Accurate in Its Ability to Make