Activation of zymogens or proenzymes is often accomplished by

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Zymogens or proenzymes are inactive precursors of enzymes that need to be cleaved, usually by specific proteases, to become active. This process is called proteolytic activation or proteolysis. Hydrolysis of the peptide chain at specific sites within the zymogen/proenzyme structure is the most common way to activate these molecules, resulting in a conformational change that exposes the active site and allows substrate binding and catalysis.

Activation of Zymogens or Proenzymes Is Often Accomplished by