Proteins are "tagged" for degradation by cytosolic proteases such as calpains through the covalent attachment of

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Quizplus · Accepted Answer

Ubiquitin is a small protein that is covalently attached to target proteins by a series of enzymes, resulting in a "ubiquitin tag". This tag signals the protein degradation machinery to degrade the tagged protein. Calpains are cytosolic proteases that can degrade ubiquitinated proteins. Glutathione, glucose, pyridoxal phosphate, and clathrin are not involved in this process.

Proteins Are "Tagged" for Degradation by Cytosolic Proteases Such as Calpains