The Maximal Velocity (Vmax) of the Acetyl-CoA Carboxylase Reaction Would

The maximal velocity (Vmax) of the acetyl-CoA carboxylase reaction would be obtained when

A) acetyl-CoA carboxylase is present in excess of acetyl-CoA.
B) the acetyl-CoA, carbon dioxide, and ATP concentrations are all saturating.
C) the concentration of enzyme-bound biotin equals the carbon dioxide concentration.
D) the reaction is first-order with respect to acetyl-CoA.
E) initial rates are measured at any acetyl-CoA concentration, since Vmax, but not Km, is independent of substrate concentration.