Regarding triacylglycerol (TG) breakdown/hydrolysis, which one of the statements is false?
A) Pancreatic lipase hydrolyzes TG in the intestinal lumen to 2?monoacylglycerols plus two fatty acids and its activity is enhanced by colipase.
B) There is a hormone sensitive lipase in adipocytes whose function is fatty acid mobilization.
C) Fatty acid mobilization via this enzyme can be altered as the diet is changed.
D) Glucagon stimulates this hormone sensitive lipase by inhibiting adenylate cyclase and lowering cAMP allowing the enzyme to become dephosphorylated which, is its active form.
E) Of the fatty acids eventually released from total hydrolysis of TG in the adipocyte, some enter the blood as free fatty acids where they bind albumin and are carried to other tissues such as muscle.
Correct Answer:
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