Specificity in the action of a peptide hormone is determined at the level of

Question

Quizplus · Accepted Answer

Specificity in the action of a peptide hormone is determined at the level of the receptor and the substrates to be phosphorylated. Peptide hormones bind to specific receptors on the surface of target cells, and the activation of these receptors triggers signaling pathways that lead to the phosphorylation and activation of specific target proteins. The specificity of the response depends on the specific receptor and the specific set of substrates that can be phosphorylated by the associated signaling pathways. Cyclic AMP and the cyclic AMP-dependent protein kinase are important components of many signaling pathways, but their role is more related to the amplification and propagation of the signal, rather than the specificity of the response.

Specificity in the Action of a Peptide Hormone Is Determined