Which of the Following Represents an Enzyme-Catalyzed Reaction? (E = $\to$

Which of the following represents an enzyme-catalyzed reaction? (E = enzyme, P = product, S = substrate)

A) E + P $\to$ E + S
B) E + S $\to$ E + P
C) E + S $\to$ P
D) E + S $\to$ E
E) P + S $\to$ E