In hierarchical sequencing, what role do bacterial artificial chromosomes play?
A) They are used to amplify and maintain copies of a given sequence.
B) They are used to determine the chromosomal location of a given sequence fragment.
C) They are used to break DNA into fragments.
D) Each one contains a genomic library.
E) None of the above; bacterial artificial chromosomes are not used in hierarchical sequencing.

Question

Quizplus · Accepted Answer

Bacterial artificial chromosomes (BACs) are used to amplify and maintain copies of large DNA fragments, which are then sequenced in hierarchical sequencing.

In Hierarchical Sequencing, What Role Do Bacterial Artificial Chromosomes Play