Duplications and translocations differ in that
A) translocations involve the loss of a chromosomal segment, whereas duplications involve addition of an entire chromosome.
B) duplications involve the breakage and swapping of DNA segments on homologous chromosomes, whereas translocations are reciprocal exchanges on nonhomologous chromosomes.
C) translocations involve the breakage and insertion of DNA segments in reverse order, whereas duplications are the breakage at different points on the chromosome.
D) duplications lead to duplications of the chromosome, whereas translocations involve swapping of chromosome segments.
E) translocations result in loss of chromosomal segments, whereas duplications result in significant additions to nonhomologous chromosomes.

Question

Quizplus · Accepted Answer

Duplications involve the addition of extra copies of a DNA segment, whereas translocations involve the exchange of DNA segments between nonhomologous chromosomes. These exchanges are often reciprocal (meaning that both chromosomes involved in the translocation swap a segment of DNA), and they do not necessarily involve the loss of any genetic material. In contrast, duplications do not involve the swapping of material between homologous chromosomes. Instead, duplications can arise through a number of mechanisms, including errors in DNA replication or recombination, and they result in an extra copy of all or part of a chromosome.

Duplications and Translocations Differ in That