Which one of these molecules can be a reactant in a Friedel-Crafts reaction?
A)Aniline
B)Benzenesulfonic acid
C)Chloroethene
D)Bromobenzene
E)p-Bromonitrobenzene

Question

Quizplus · Accepted Answer

Friedel-Crafts reaction involves the acylation or alkylation of an aromatic ring using a Lewis acid catalyst. Bromobenzene is an aromatic compound that can undergo Friedel-Crafts reaction with an appropriate electrophile and catalyst. Aniline (A) has a primary amine group, which can react with the catalyst and form an unwanted side product. Benzenesulfonic acid (B) is not an electrophile and cannot undergo Friedel-Crafts reaction without first being converted into an electrophile. Chloroethene (C) is not an aromatic compound, and therefore, cannot undergo Friedel-Crafts reaction. p-Bromonitrobenzene (E) has a strong electron-withdrawing group (-NO2), which deactivates the aromatic ring towards electrophilic substitution and therefore, is not a good choice for Friedel-Crafts reaction.

Which One of These Molecules Can Be a Reactant in a Friedel-Crafts