A dominant mechanism for control of eukaryotic peptide chain initiation is:

Question

Quizplus · Accepted Answer

Phosphorylation/dephosphorylation is a well-established mechanism for control of eukaryotic peptide chain initiation. This process involves the phosphorylation of the eukaryotic initiation factor 2alpha (eIF2alpha) by a kinase enzyme, which leads to inhibition of protein synthesis initiation. Dephosphorylation of eIF2alpha by a phosphatase enzyme releases this inhibition and leads to resumption of protein synthesis initiation. This process is important for regulating protein synthesis in response to various environmental stresses.

A Dominant Mechanism for Control of Eukaryotic Peptide Chain Initiation