Enzymes that acetylate the ε-amino group of lysine in the histidine tails are called ____ and are involved in ____.
A) histone deacetylases; restoring chromatin to a repressed state
B) histone acetyltransferases (HATs); initial events in transcriptional activation
C) histone activases; formation of the de-repression complex
D) Schiff base formation; promoting the formation of closed complexes
E) none of the above

Question

Quizplus · Accepted Answer

Histone acetyltransferases (HATs) acetylate the ε-amino group of lysine in the histidine tails and are involved in the initial events of transcriptional activation. Histone deacetylases, on the other hand, remove acetyl groups and are involved in restoring chromatin to a repressed state. Histone activases and Schiff base formation are not correct terms for this process.

Enzymes That Acetylate the ε-Amino Group of Lysine in the Histidine