AZT (3'-azido-2',3'-dideoxythymidine) is a drug that gets incorporated into growing viral DNA and blocks the activity of:

Question

Quizplus · Accepted Answer

AZT is a nucleoside analogue that gets incorporated into the growing viral DNA chain by reverse transcriptase, a viral enzyme that synthesizes DNA from RNA. Once incorporated into the DNA chain, it acts as a chain terminator, preventing further elongation of the chain. This inhibition of reverse transcriptase activity ultimately prevents the replication of the virus. AZT does not affect DNA ligase or DNA polymerase α and β.

AZT (3'-Azido-2',3'-Dideoxythymidine) Is a Drug That Gets Incorporated into Growing