All are characteristics of leptin EXCEPT:
A) it binds to hypothalamus, inhibits release of neuropeptide-Y and is thus an anorexic agent.
B) it is a signal molecule that limits food intake and increases energy expenditure.
C) it communicates the status of triacylglycerol levels in the adipocytes to the central nervous system.
D) if leptin levels are low, appetite is suppressed; and if leptin levels are high, appetite is increased.
E) it induces synthesis of β-oxidation enzymes and increases expression of uncoupler protein-2 (UCP-2) to increase thermogenesis.
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