Energy balance in the cell (ATP/ADP/AMP levels) is an important factor in the metabolic pathways we have studied. How does this regulation take place?
A) ATP, ADP and/or AMP bind to DNA to modulate transcription of genes for enzymes involved in metabolism
B) ATP, ADP and/or AMP bind to enzymes involved in metabolism, allosterically changing the enzyme activity
C) High levels of ATP result in nonenzymatic phosphorylation of the enzymes involved in metabolism, changing their activity
D) High levels of ATP result in excessive production of cyclic AMP, causing activation of pathways such as glycogenolysis and gluconeogenesis
E) None of the above

Question

Quizplus · Accepted Answer

ATP, ADP and/or AMP bind to enzymes involved in metabolism, allosterically changing the enzyme activity. This regulation occurs due to the changes in the shape and activity of the enzyme induced by binding to these molecules. High levels of ATP inhibit glycolysis, while low levels of ATP stimulate it. Similarly, high levels of ADP and AMP activate glycolysis, promoting the formation of ATP. This regulation is important for maintaining cellular energy balance and ensuring that metabolic pathways are activated or inhibited as necessary.

Energy Balance in the Cell (ATP/ADP/AMP Levels) Is an Important