Inhibition of the citric acid cycle at isocitrate dehydrogenase increases the levels of citrate and isocitrate that may increase the production of:

Question

Quizplus · Accepted Answer

Inhibition of isocitrate dehydrogenase results in the accumulation of citrate and isocitrate, which can be used to synthesize cytosolic acetyl-CoA and glyoxylate through the action of the enzyme ATP citrate lyase. These molecules are important for lipid biosynthesis and gluconeogenesis. The other options are not directly linked to the accumulation of citrate and isocitrate.

Inhibition of the Citric Acid Cycle at Isocitrate Dehydrogenase Increases