Substrate-level phosphorylation occurs in glycolysis in the reaction catalyzed by ____ and belongs to ____ class of enzymes.

Question

Quizplus · Accepted Answer

Substrate-level phosphorylation refers to a type of phosphorylation where a phosphate group is transferred from a phosphorylated substrate to ADP to form ATP. In glycolysis, there are two reactions that involve substrate-level phosphorylation, both of which are catalyzed by transferases. The first of these reactions is catalyzed by hexokinase, in which ATP is used to phosphorylate glucose to form glucose-6-phosphate. The second reaction is catalyzed by phosphoglycerate kinase, in which ADP is phosphorylated using 1,3-bisphosphoglycerate to form ATP and 3-phosphoglycerate. However, only choice A correctly identifies the enzyme and the class of enzyme responsible for the substrate-level phosphorylation that occurs in glycolysis.

Substrate-Level Phosphorylation Occurs in Glycolysis in the Reaction Catalyzed by ____