Which of the following is true regarding the Briggs and Haldane steady state assumption?
A) It is defined by the equation
B) It states the rate of enzyme-substrate complex formation differs from the rate of enzyme-substrate disappearance.
C) The concentration of the enzyme-substrate complex reaches a constant value even in a dynamic system.
D) The enzyme-substrate complex will always dissociate to form E + P.
E) The total amount of enzyme is variable, depending on the amount of substrate available.

Question

Which of the following is true regarding the Briggs and Haldane steady state assumption?
A) It is defined by the equation 
B) It states the rate of enzyme-substrate complex formation differs from the rate of enzyme-substrate disappearance. 
C) The concentration of the enzyme-substrate complex reaches a constant value even in a dynamic system. 
D) The enzyme-substrate complex will always dissociate to form E + P. 
E) The total amount of enzyme is variable, depending on the amount of substrate available.

Quizplus · Accepted Answer

The Briggs and Haldane steady state assumption states that the concentration of the enzyme-substrate complex reaches a constant value even in a dynamic system, which is reflected in the equation given in choice A. It does not state that the rate of enzyme-substrate complex formation differs from the rate of enzyme-substrate disappearance, as in choice B. It also does not state that the enzyme-substrate complex will always dissociate to form E + P, as in choice D. Finally, it does not imply that the total amount of enzyme is variable, depending on the amount of substrate available, as in choice E.

Which of the Following Is True Regarding the Briggs and Haldane