Which of the following mutations would probably be least likely to impact the function of the protein?
A) Lys to Ser
B) Ala to Asp
C) His to Pro
D) Val to Ile
E) Phe to Tyr

Question

Quizplus · Accepted Answer

Valine and Isoleucine only differ in the location of a single methyl group and have very similar chemical properties, thus a mutation from one to the other is unlikely to significantly impact protein function. The other mutations could potentially alter the chemical properties and function of the protein.

Which of the Following Mutations Would Probably Be Least Likely