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Which of the Following Statements About the Proposed Mechanisms of Action

Question 11

Multiple Choice

Which of the following statements about the proposed mechanisms of action for hen egg white lysozyme does NOT support either model?


A) Glycosidic bond cleavage occurs by general acid/base catalysis.
B) A covalent intermediate is formed between an active site aspartate and C1 of the substrate.
C) A water molecule is deprotonated, which then attacks C1 of the substrate.
D) The active site aspartic acid changes between being protonated and deprotonated.
E) The active site glutamic acid changes between being protonated and deprotonated.

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