Catabolite or glucose repression of the lac operon is a regulatory system, which depends on the levels of cAMP in the cell.

Question

Quizplus · Accepted Answer

Catabolite or glucose repression of the lac operon is indeed a regulatory system that relies on the levels of cAMP in the cell. More specifically, when glucose levels are high, cAMP levels decrease, and this reduces the binding of cAMP-CRP (cAMP receptor protein) to the promoter region of the lac operon, thus decreasing the transcription of genes in the operon. This phenomenon is called catabolite repression or glucose repression.

Catabolite or Glucose Repression of the Lac Operon Is a Regulatory