One substrate level phosphorylation occurs in the citric acid cycle in the reaction catalyzed by:
A) α-ketoglutarate dehydrogenase.
B) succinate dehydrogenase.
C) succinyl -CoA synthetase.
D) isocitrate dehydrogenase.
E) citrate synthase.

Question

Quizplus · Accepted Answer

Succinyl-CoA synthetase catalyzes the conversion of succinyl-CoA to succinate and uses the energy released to phosphorylate ADP to ATP, representing a substrate-level phosphorylation in the citric acid cycle. The other enzymes listed do not catalyze reactions that involve substrate-level phosphorylation.

One Substrate Level Phosphorylation Occurs in the Citric Acid Cycle