A client that you are caring for has advanced kidney disease and is about to commence drug therapy.In order to maintain safe plasma drug levels,the prescriber might have to consider:

Question

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As the client has advanced kidney disease, their renal function may be compromised, leading to decreased drug metabolism and excretion. Therefore, the prescriber may need to decrease the dosage of the drug to maintain safe plasma drug levels and prevent toxicity. Increasing the dosage (A) or increasing the dose and frequency of administration (D) could lead to increased levels of the drug, increasing the risk of toxicity. Increasing the frequency of dosing (C) would not necessarily address the issue of decreased drug metabolism and excretion and may also increase the risk of toxicity.

A Client That You Are Caring for Has Advanced Kidney