You study two cell lines.In one,the MDM2 protein is overexpressed; in the other the p53 protein is absent.What difference would you expect in the behavior of these two cell lines?
A) In cells containing overexpressed MDM2,p53 levels will be low; in cells lacking the TP53 gene,p53 levels are also low; thus there is no difference in behavior.
B) In cells containing overexpressed MDM2,p53 levels will be high; in cells lacking the TP53 gene,p53 levels are low; thus there is a drastic difference in behavior.
C) In cells containing overexpressed MDM2,p53 levels will be high; in cells lacking the TP53 gene,p53 levels are high; thus there is no difference.
D) In cells containing overexpressed MDM2,p53 levels will be low; in cells lacking the TP53 gene,p53 levels are high; thus there is no drastic difference.
E) None of these are correct.
Correct Answer:
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