The progression of HIV infection to AIDS is most directly due to which of the following?
A)A loss of CD4+ T cells to numbers insufficient to prevent infections
B)Reduction in serum IgG levels to levels insufficient to prevent infections
C)Increased amount of virus in the blood
D)Loss of weight
E)Reduction in CD8+ CTLs specific for HIV

Question

Quizplus · Accepted Answer

AIDS is most often diagnosed based on a finding of a CD4+ T cell count below 200 cells/mm and certain opportunistic infections.The incidence of infections,and other manifestations of AIDS including cancers,weight loss,encephalopathy increase significantly when the blood CD4+ T cell count drops,which reflects an even greater loss of T cells in lymphoid organs.

The Progression of HIV Infection to AIDS Is Most Directly