Which molecules on the T cell surface are directly involved in HIV infection?
A)CD4 and CD25
B)CCR5 and CD25
C)CD3 and CD4
D)CD8 and CCR5
E)CD4 and CCR5

Question

Quizplus · Accepted Answer

The HIV virus infects CD4+ T cells by a mechanism that involves the HIV envelope gp120 protein binding to CD4,followed by conformational changes in gp120 promoting CCR5 binding.The importance of CCR5 is indicated by the fact that of rare individuals who lack CCR5 are resistant to HIV infection.

Which Molecules on the T Cell Surface Are Directly Involved