The tumor necrosis factor (TNF)family of proteins includes several soluble and membrane proteins that share structural homologies.All members of this family bind to members of the TNF-receptor family of molecules expressed on cell surfaces.TNF-R family members are structurally homologous to one another and utilize similar signal transduction pathways.
For each description of a TNF or a TNF-R family member in questions ,select the term listed in options A-E that best matches it.
-Expressed as a membrane molecule on the surface of activated T cells,it binds to a receptor found on many cell types,including T cells,and induces apoptosis.

Question

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Fas ligand (FasL,CD178)is a member of the tumor necrosis factor family and binds Fas on T cells and other cell types.Fas-Fas ligand-dependent apoptosis of T cells is important for T cell homeostasis;deficiencies in Fas or FasL cause autoimmune disease.

The Tumor Necrosis Factor (TNF)family of Proteins Includes Several Soluble