Once B cells begin secreting antibodies, they cease dividing and have a life-span of only a few days.

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Once B cells begin secreting antibodies, they differentiate into either memory B cells or plasma cells. Plasma cells continue to secrete large amounts of antibodies for a short period of time (a few days to a few weeks) before they undergo apoptosis. However, memory B cells can survive for a long time (many years) and can quickly activate into plasma cells if the same pathogen is encountered again.

Once B Cells Begin Secreting Antibodies, They Cease Dividing and Have