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Naive T Cells Are Isolated and Left Untreated or Treated

Question 20

Multiple Choice

Naive T cells are isolated and left untreated or treated with 'compound X' for 1 hour. Following this, the T cells are incubated with a range of concentrations of a soluble form of ICAM-1 that has been conjugated to a fluorescent dye (soluble-ICAM-1-FITC) . Fifteen minutes later, the cells are washed, and the relative amount of fluorescence bound to the cells is measured. The results of this assay are shown in Figure Q6) . Naive T cells are isolated and left untreated or treated with 'compound X' for 1 hour. Following this, the T cells are incubated with a range of concentrations of a soluble form of ICAM-1 that has been conjugated to a fluorescent dye (soluble-ICAM-1-FITC) . Fifteen minutes later, the cells are washed, and the relative amount of fluorescence bound to the cells is measured. The results of this assay are shown in Figure Q6) .   Figure Q6)  The most likely identity of compound X is: A)  The adhesion molecule, LFA-1 B)  The adhesion molecule, L-selectin C)  The sulfated carbohydrate structure, sulfated sialyl-Lewis<sup>X</sup> D)  The chemokine ligand for CCR7 E)  The immunoglobulin superfamily member, CD2 Figure Q6) The most likely identity of compound X is:


A) The adhesion molecule, LFA-1
B) The adhesion molecule, L-selectin
C) The sulfated carbohydrate structure, sulfated sialyl-LewisX
D) The chemokine ligand for CCR7
E) The immunoglobulin superfamily member, CD2

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