B-1 B cells are considered a component of the innate rather than the adaptive immune response. The antibodies produced by B-1 B cells generally recognize capsular polysaccharide antigens found on many bacteria and viruses. These antibodies are considered part of the innate immune response because:
A) They recognize pathogens rather than innocuous harmless antigens.
B) They are produced prior to the exposure to the pathogen.
C) They are specific for carbohydrate rather than protein antigens.
D) They are secreted by B-1 B cells starting at 48 hour post-infection.
E) They are not generated by the process of VD-J recombination of immunoglobulin genes.

Question

Quizplus · Accepted Answer

B-1 B cells are considered a component of the innate immunity because they produce antibodies prior to exposure to the pathogen. These antibodies are not generated by the process of VD-J recombination of immunoglobulin genes, and recognize capsular polysaccharide antigens found on many bacteria and viruses. This recognition of the pathogens rather than innocuous harmless antigens makes them part of the innate immune response. However, the specificity of these antibodies for carbohydrate rather than protein antigens does not necessarily make them part of the innate immunity. The secretion of these antibodies by B-1 B cells starting at 48 hour post-infection is not a defining characteristic of the innate immunity.

B-1 B Cells Are Considered a Component of the Innate