Using an antibody that recognizes the phosphorylated, but not the non-phosphorylated form of the transcription factor, NFAT, T cells are permeabilized, stained with this antibody, and analyzed by flow cytometry. Which of the data in Figure represent the expected pattern of staining from wild-type T cells before and after TCR stimulation.
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Q8: The TCR signaling module leading to
Q9: Small GTPases, such as Ras, Rho, and
Q10: Several small GTPases play critical roles in
Q11: The TCR and BCR are multi-subunit receptor
Q12: Second messengers, such as calcium ions (Ca2+),
Q14: Following TCR or BCR signaling, the most
Q15: All of the modular protein domains used
Q16: Human patients with genetic defects that result
Q17: The TCR and BCR are each composed
Q18: Scaffold proteins are often phosphorylated at multiple
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