Solved

The Immunosuppressive Drug Rapamycin Acts by Inhibiting MTOR

Question 40

Multiple Choice

The immunosuppressive drug rapamycin acts by inhibiting mTOR. When activated T cells are treated with rapamycin in a cell culture assay, they show greatly diminished proliferation, and accumulate to much lower numbers than control-treated cells. This is because:


A) Rapamycin inhibits cells from increasing their synthesis of lipids and proteins.
B) Rapamycin inhibits cells from activating the pro-survival protein, Bcl-2.
C) Rapamycin inhibits DNA synthesis in activated T cells.
D) Rapamycin inhibits cell cycle progression in activated T cells.
E) Rapamycin inhibits the T cell's production of the growth factor, IL-2.

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