The mechanism of cross-presentation by dendritic cells is an essential pathway for generating CD8 T cell responses to some intracellular pathogens. If this pathway did not exist, we would be highly susceptible to:
A) Intracellular pathogens that can survive inside macrophage endocytic vesicles
B) Intracellular pathogens that are able to evade antibody responses
C) Intracellular pathogens that do not infect and replicate in dendritic cells
D) Intracellular pathogens that can spread from cell to cell by inducing cell fusion
E) Intracellular pathogens that infect and replicate in red blood cells

Question

Quizplus · Accepted Answer

Cross-presentation by dendritic cells is specifically important for generating CD8 T cell responses to intracellular pathogens that do not infect and replicate in dendritic cells. Therefore, if this pathway did not exist, we would be highly susceptible to such pathogens. Option A is incorrect because macrophages have their own mechanisms for processing and presenting antigens to CD8 T cells. Option B is unrelated to cross-presentation by dendritic cells. Option D and E are also unrelated as they describe different modes of pathogen spread and infectivity.

The Mechanism of Cross-Presentation by Dendritic Cells Is an Essential