T cells expressing $\gamma$:$\delta$ TCRs are distinct from those expressing $\alpha$:$\beta$ TCRs in that they do not generally recognize host cell responses to infections or tissue damage; rather they recognize components of the pathogen directly.

Question

Quizplus · Accepted Answer

T cells expressing F1F1F1S1F1F1F10:F1F1F1S1F1F1F10 TCRs are known as unconventional T cells, which recognize pathogen-derived antigens directly rather than host cell responses to infections or tissue damage. On the other hand, T cells expressing F1F1F1S1F1F1F10:F1F1F1S1F1F1F10 TCRs are conventional T cells that recognize antigenic peptide fragments presented by MHC molecules on infected or damaged host cells.

T Cells Expressing γ\gammaγ δ\deltaδ TCRs Are Distinct from Those Expressing α\alphaα

T Cells Expressing $\gamma$ $\delta$ TCRs Are Distinct from Those Expressing $\alpha$