The mucosal tissues of the body have their own unique set of immune structures that function as sites for initiating adaptive immune responses. The necessity for mucosa-associated lymphoid tissues to have unique cell types (M cells) and structures is because:
A) The mucous layer lining mucosal surfaces makes it difficult for normal antigen-presenting cells to function.
B) The epithelial surfaces that line the gut, lungs, and nasal passages prevent antigen-presenting cells from accessing microbes and microbial products.
C) The epithelial cells found in mucosal tissues are distinct from those that provide barrier functions to the skin.
D) Mucosal sites, where most pathogens access the body, are exposed to vast numbers of diverse microbes.
E) Mucosal tissues lack innate sensor cells that can respond to PAMPs and provide short-term innate immune protection.

Question

Quizplus · Accepted Answer

Mucosal sites are exposed to a vast number of diverse microbes, necessitating specialized immune structures and cells like M cells to efficiently sample and respond to antigens.

The Mucosal Tissues of the Body Have Their Own Unique