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T Cells Expressing the Co-Receptor CD8 Are Generally Cytotoxic Cells

Question 35

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T cells expressing the co-receptor CD8 are generally cytotoxic cells, with an important function in eliminating virus infections that can occur in many different cell types and tissues. In contrast, CD4 T cells directly interact with a very restricted set of cells, such as dendritic cells, macrophages, and B cells. Describe one important mechanism that accounts for this division of labor between CD8 and CD4 T cells.

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CD8 T cells recognize antigenic peptides...

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